Publications 2018

1. Operti MC, Fecher D, van Dinther EAW, Grimm S, Jaber R, Figdor CG, Tagit O. A comparative assessment of continuous production techniques to generate sub-micron size PLGA particles. Int J Pharm, 2018. 550(1-2): 140-8.

2. Wouters H, van der Klauw MM, de Witte T, Stauder R, Swinkels DW, Wolffenbuttel BHR, Huls G. Association of anemia with health-related quality of life and survival: a large population-based cohort study. Haematologica, 2018.

3. Meddens MBM, Mennens SFB, Celikkol FB, te Riet J, Kanger JS, Joosten B, Witsenburg JD, Brock R, Figdor CG, Cambi A. Biophysical Characterization of CD6-TCR/CD3 Interplay in T Cells. Front Immunol, 2018. 9:

4. de Winde CM, Matthews AL, van Deventer S, van der Schaaf A, Tomlinson ND, Jansen E, Eble JA, Nieswandt B, McGettrick HM, Figdor CG, Tomlinson MG, Acton SE, van Spriel AB. C-type lectin-like receptor 2 (CLEC-2)-dependent dendritic cell migration is controlled by tetraspanin CD37. J Cell Sci, 2018. 131(19): jcs214551.

5. Fruhwirth GO, Kneilling M, de Vries IJM, Weigelin B, Srinivas M, Aarntzen E. The Potential of In Vivo Imaging for Optimization of Molecular and Cellular Anti-cancer Immunotherapies. Mol Imaging Biol, 2018. 20(5): 696-704.

6. Baron F, Stevens-Kroef M, Kicinski M, Meloni G, Muus P, Marie JP, Halkes CJM, Thomas X, Vrhovac R, Specchia G, Lefrere F, Sr., Sica S, Mancini M, Venditti A, Hagemeijer A, Becker H, Jansen JH, Amadori S, de Witte T, Willemze R, Suciu S. Cytogenetic clonal heterogeneity is not an independent prognosis factor in 15-60-year-old AML patients: results on 1291 patients included in the EORTC/GIMEMA AML-10 and AML-12 trials. Ann Hematol, 2018. 97(10): 1785-95.

7. Roelofsen T, Wefers C, Gorris MAJ, Textor JC, Massuger LFAG, de Vries IJM, van Altena AM. Spontaneous Regression of Ovarian Carcinoma After Septic Peritonitis; A Unique Case Report. Frontiers in Oncology, 2018. 8: 562.

8. Weiden J, Voerman D, Dolen Y, Das RK, van Duffelen A, Hammink R, Eggermont LJ, Rowan AE, Tel J, Figdor CG. Injectable Biomimetic Hydrogels as Tools for Efficient T Cell Expansion and Delivery. Front Immunol, 2018. 9: 2798.

9. Bloemendal M, Rietveld MJA, van Willigen WW, Gerritsen WR, Figdor CG, Bonenkamp JJ, Westdorp H, Boudewijns S, Koornstra RHT, Adang EMM, Schreibelt G, Ottevanger PB, de Vries IJM, Bol KF. Health-related quality of life analysis in stage III melanoma patients treated with adjuvant dendritic cell therapy. Clin Transl Oncol, 2018.

10. Constantinides C, McNeill E, Carnicer R, Al Haj Zen A, Urruela RS, Shaw A, Patel J, Swider E, Azaloian R, Potamiti L, Hadjisavvas A, Padilla-Parra S, Kyriacou K, Srinivas M, Carr CA. Improved cellular uptake of perfluorocarbon nanoparticles for in vivo murine cardiac (19)F MRS/MRI and temporal tracking of progenitor cells. Nanomedicine, 2018.

11. Platzbecker U, Fenaux P, Ades L, Giagounidis A, Santini V, van de Loosdrecht AA, Bowen D, de Witte T, Garcia-Manero G, Hellstrom-Lindberg E, Germing U, Stauder R, Malcovati L, Sekeres M, Steensma DP, Gloaguen S. Proposals for revised IWG 2018 hematological response criteria in patients with MDS included in clinical trials. Blood, 2018.

12. Ignacio BJ, Albin TJ, Esser-Kahn AP, Verdoes M. Toll-like Receptor Agonist Conjugation: A Chemical Perspective. Bioconjug Chem, 2018. 29(3): 587-603.

13. Thoemmes F, Rosseel Y, Textor J. Local fit evaluation of structural equation models using graphical criteria. Psychol Methods, 2018. 23(1): 27-41.

14. Weiden J, Tel J, Figdor CG. Synthetic immune niches for cancer immunotherapy. Nat Rev Immunol, 2018. 18(3): 212-9.

15. Le Gall CM, Weiden J, Eggermont LJ, Figdor CG. Dendritic cells in cancer immunotherapy. Nat Mater, 2018. 17(6): 474-5.

16. Stauder R, Yu G, Koinig KA, Bagguley T, Fenaux P, Symeonidis A, Sanz G, Cermak J, Mittelman M, Hellstrom-Lindberg E, Langemeijer S, Holm MS, Madry K, Malcovati L, Tatic A, Germing U, Savic A, van Marrewijk C, Guerci-Bresler A, Luno E, Droste J, Efficace F, Smith A, Bowen D, de Witte T. Health-related quality of life in lower-risk MDS patients compared with age- and sex-matched reference populations: a European LeukemiaNet study. Leukemia, 2018. 32(6): 1380-92.

17. Rops A, Jansen E, van der Schaaf A, Pieterse E, Rother N, Hofstra J, Dijkman H, van de Logt AE, Wetzels J, van der Vlag J, van Spriel AB. Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice. Kidney Int, 2018. 93(6): 1356-66.

18. Swider E, Koshkina O, Tel J, Cruz LJ, de Vries IJM, Srinivas M. Customizing poly(lactic-co-glycolic acid) particles for biomedical applications. Acta Biomater, 2018. 73: 38-51.

19. Stahl M, DeVeaux M, de Witte T, Neukirchen J, Sekeres MA, Brunner AM, Roboz GJ, Steensma DP, Bhatt VR, Platzbecker U, Cluzeau T, Prata PH, Itzykson R, Fenaux P, Fathi AT, Smith A, Germing U, Ritchie EK, Verma V, Nazha A, Maciejewski JP, Podoltsev NA, Prebet T, Santini V, Gore SD, Komrokji RS, Zeidan AM. The use of immunosuppressive therapy in MDS: clinical outcomes and their predictors in a large international patient cohort. 2018. 2(14): 1765-72.

20. Textor J, Fahnrich A, Meinhardt M, Tune C, Klein S, Pagel R, Konig P, Kalies K, Westermann J. Deep Sequencing Reveals Transient Segregation of T Cell Repertoires in Splenic T Cell Zones during an Immune Response. J Immunol, 2018. 201(2): 350-8.

21. Grand MK, de Witte TJM, Putter H. Dynamic prediction of cumulative incidence functions by direct binomial regression. Biom J, 2018. 60(4): 734-47.

22. Arnold KF, Ellison G, Gadd SC, Textor J, Tennant P, Heppenstall A, Gilthorpe MS. Adjustment for time-invariant and time-varying confounders in 'unexplained residuals' models for longitudinal data within a causal framework and associated challenges. Stat Methods Med Res, 2018. 962280218756158.

23. Gorris MAJ, Halilovic A, Rabold K, van Duffelen A, Wickramasinghe IN, Verweij D, Wortel IMN, Textor JC, de Vries IJM, Figdor CG. Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment. J Immunol, 2018. 200(1): 347-54.

24. de Swart L, Reiniers C, Bagguley T, van Marrewijk C, Bowen D, Hellstrom-Lindberg E, Tatic A, Symeonidis A, Huls G, Cermak J, van de Loosdrecht AA, Garelius H, Culligan D, Macheta M, Spanoudakis M, Panagiotidis P, Krejci M, Blijlevens N, Langemeijer S, Droste J, Swinkels DW, Smith A, de Witte T, Committee ES. Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromes. Haematologica, 2018. 103(1): 69-79.

25. Schmid C, de Wreede LC, van Biezen A, Finke J, Ehninger G, Ganser A, Volin L, Niederwieser D, Beelen D, Alessandrino P, Kanz L, Schleuning M, Passweg J, Veelken H, Maertens J, Cornelissen JJ, Blaise D, Gramatzki M, Milpied N, Yakoub-Agha I, Mufti G, Rovira M, Arnold R, de Witte T, Robin M, Kroger N. Outcome after relapse of myelodysplastic syndrome and secondary acute myeloid leukemia following allogeneic stem cell transplantation: a retrospective registry analysis on 698 patients by the Chronic Malignancies Working Party of the European Society of Blood and Marrow Transplantation. Haematologica, 2018. 103(2): 237-45.

26. van Dalen FJ, van Stevendaal M, Fennemann FL, Verdoes M, Ilina O. Molecular Repolarisation of Tumour-Associated Macrophages. Molecules, 2018. 24(1):

27. Baron F, Stevens-Kroef M, Kicinski M, Meloni G, Muus P, Marie JP, Halkes CJM, Thomas X, Vrhovac R, Albano F, Lefrere F, Sica S, Mancini M, Venditti A, Hagemeijer A, Jansen JH, Amadori S, de Witte T, Willemze R, Suciu S. Impact of Induction Regimen and of Allogeneic Hematopoietic Cell Transplantation on Outcome in Younger Adults Patients with Acute Myeloid Leukemia with a Monosomal Karyotype. 2018.

28. Galisova A, Herynek V, Swider E, Sticova E, Patikova A, Kosinova L, Kriz J, Hajek M, Srinivas M, Jirak D. A Trimodal Imaging Platform for Tracking Viable Transplanted Pancreatic Islets In Vivo: F-19 MR, Fluorescence, and Bioluminescence Imaging. Mol Imaging Biol, 2018.

29. Itzykson R, Crouch S, Travaglino E, Smith A, Symeonidis A, Hellstrom-Lindberg E, Sanz G, Cermak J, Stauder R, Elena C, Germing U, Mittelman M, Langemeijer S, Madry K, Tatic A, Holm MS, Almeida AM, Savic A, Simec NG, Luno E, Culligan D, Guerci-Bresler A, Malcovati L, van Marrewijk C, Bowen D, de Witte T, Fenaux P, European MDSRm. Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes. Blood Adv, 2018. 2(16): 2079-89.

30. Wimmers F, Subedi N, van Buuringen N, Heister D, Vivie J, Beeren-Reinieren I, Woestenenk R, Dolstra H, Piruska A, Jacobs JFM, van Oudenaarden A, Figdor CG, Huck WTS, de Vries IJM, Tel J. Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells. Nat Commun, 2018. 9(1): 3317.

31. Constantinides C, Basnett P, Lukasiewicz B, Carnicer R, Swider E, Majid QA, Srinivas M, Carr CA, Roy I. In Vivo Tracking and (1)H/(19)F Magnetic Resonance Imaging of Biodegradable Polyhydroxyalkanoate/Polycaprolactone Blend Scaffolds Seeded with Labeled Cardiac Stem Cells. ACS Appl Mater Interfaces, 2018. 10(30): 25056-68.

32. de Swart L, Smith A, Haase D, Fenaux P, Symeonidis A, Cermak J, Sanz G, Stauder R, Mittelman M, Hellstrom-Lindberg E, Malcovati L, Langemeijer S, Skov-Holm M, Madry K, Germing U, Almeida AM, Tatic A, Savic A, Simec NG, van Marrewijk C, Guerci-Bresler A, Sanhes L, Luno E, Culligan D, Beyne-Rauzy O, Burgstaller S, Blijlevens N, Bowen D, de Witte T. Prognostic impact of a suboptimal number of analyzed metaphases in normal karyotype lower-risk MDS. Leuk Res, 2018. 67: 21-6.

33. Qiu L, Valente M, Dolen Y, Jager E, Beest MT, Zheng L, Figdor CG, Verdoes M. Endolysosomal-Escape Nanovaccines through Adjuvant-Induced Tumor Antigen Assembly for Enhanced Effector CD8(+) T Cell Activation. Small, 2018. 14(15): e1703539.

34. Perkovic E, Textor J, Kalisch M, Maathuis MH. Complete Graphical Characterization and Construction of Adjustment Sets in Markov Equivalence Classes of Ancestral Graphs. Journal of Machine Learning Research, 2018. 18:

35. Swider E, Daoudi K, Staal AHJ, Koshkina O, van Riessen NK, van Dinther E, de Vries IJM, de Korte CL, Srinivas M. Clinically-Applicable Perfluorocarbon-Loaded Nanoparticles For In vivo Photoacoustic, (19)F Magnetic Resonance And Fluorescent Imaging. Nanotheranostics, 2018. 2(3): 258-68.

36. Swider E, Staal AHJ, van Riessen NK, Jacobs L, White PB, Fokkink R, Janssen GJ, van Dinther E, Figdor CG, de Vries IJM, Koshkina O, Srinivas M. Design of triphasic poly(lactic-co-glycolic acid) nanoparticles containing a perfluorocarbon phase for biomedical applications. Rsc Advances, 2018. 8(12): 6460-70.

37. Schaper F, van Spriel AB. Antitumor Immunity Is Controlled by Tetraspanin Proteins. Front Immunol, 2018. 9: 1185.

38. Constantinides C, Maguire M, McNeill E, Carnicer R, Swider E, Srinivas M, Carr CA, Schneider JE. Fast, quantitative, murine cardiac 19F MRI/MRS of PFCE-labeled progenitor stem cells and macrophages at 9.4T. PLoS One, 2018. 13(1): e0190558.